Obesity and Diabetes Week

Diabetes & Obesity - Neuronal PTP1B regulates body weight, adiposity, and leptin action

Endocrinology - Appetite regulatory hormone responses to various dietary proteins differ by body mass index

Insulin Resistance - Cerebrocortical response to hyperinsulinemia is reduced in overweight humans

Obesity Pathogenesis - In obese, Tanner stage G1PH1 boys the inhibin B/FSH axis is activated early

Type 2 Diabetes - Obesity is a determinant of C-reactive protein levels and metabolic syndrome link in diabetes

Adipocytes - Sennidin stimulates glucose incorporation in rat adipocytes

Alstrom Syndrome - In Alstrom syndrome, obesity measures decrease but insulin resistance increases with age

Anorexia Nervosa - Weight gain enhances bone mineral density recovery in women with anorexia nervosa

Awards - Eurand announces winners of 2006 Eurand Award Program

Awards - Exubera hailed as innovation in prestigious European and American awards

Awards - Quality assurance group recognizes 10 health plans for bridging cultural healthcare divides

Blood Glucose - Continuous glucose-error grid analysis is not as effective as conventional glucose sensors

Blood Glucose - Noninvasive continuous glucose monitoring system has good results in home setting

Breast Cancer - Prediabetic phase may increase risk of developing breast cancer

Breast Cancer - Weight control through diet is a key factor for preventing BRCA-related breast cancer risk

Cancer Therapy - A common treatment for prostate cancer increases risk of diabetes and cardiovascular disease

Cardiovascular Disease - ER blood glucose in cardiogenic shock patients provides information for risk stratification

Cardiovascular Disease - Statin therapy safely reduces the risk of vascular events

Cardiovascular Health - Aerobic endurance training lowers blood pressure by reducing systemic vascular resistance

Chronic Heart Failure - Starting heart failure treatment with bisoprolol reduces sudden death rate 46% after a year

Collaborations - Diabetes Research Institute Foundation teams up with VitaZest Vitamin & Fruit-Enriched Water

Collaborations - Scripps Research Institute, McDonald's align to fight childhood obesity, type 2 diabetes

Contraception - Obese women may have increased risk of oral contraceptive failure

Correction - Researchers offer advice regarding nutritional supplements

Diabetes & Heart Disease - Coronary heart disease models poorly predict events in type 1 diabetes

Diabetes & Heart Disease - Diabetes mellitus prevalence among patients with myocardial infarction is increasing

Diabetes & Pneumonia - In type 2 diabetes with poor glycemic control impaired phagocytosis of Klebsiella pneumoniae seen

Diabetes Complications - Advanced glycation end products cause adverse vasculature effects in diabetes

Diabetes Complications - alpha-Lipoic acid prevents diabetes-induced atherosclerosis in mouse model

Diabetes Complications - Cerebral edema risk predicted by acidosis and abnormalities of sodium, potassium and urea

Diabetes Complications - Chronic kidney disease is a common complication of type 2 diabetes

Diabetes Complications - Crocetin inhibits leukocyte adherence to vascular endothelial cells induced by AGEs

Diabetes Complications - Diabetes associated with unusual RAGE signals is related to leukoencephalopathy

Diabetes Complications - Diabetic retinopathy in urban South Indians parallels adverse serum lipid profiles

Diabetes Complications - Esophageal dysmotility, delayed gastric emptying and neuropathy link to glucose variations

Diabetes Complications - Hepatic steatosis in diabetes may raise atherogenesis risk by altering dyslipidemia composition

Diabetes Complications - Impact of diabetes mellitus on cognitive decline appears to occur mainly before age 85

Diabetes Complications - Night-eating behaviors linked with adverse outcomes in diabetic patients

Diabetes Control - Body weight and insulin sensitivity in diabetes improved by chromium picolinate intake

Diabetes Control - Cognitive dysfunction is associated with poor diabetes control in older adults

Diabetes Control - Insulin sensitivity in type 2 diabetes may be improved by Ananas comosus L.

Diabetes Control - Negative correlation is seen between BMI and physical activity for type 2 diabetics

Diabetes Control - Poststroke hyperglycemia is common and prolonged despite treatment

Diabetes Control - Premeal-injected insulin glulisine has advantages over regular human insulin in type 1 diabetes

Diabetes Control - Reaching normoglycemia improves life expectancy and lower type 2 diabetes complication rates

Diabetes Control - Vildagliptin lowers postprandial intestinal triglyceride-rich lipoprotein particles in diabetes

Diabetes Epidemiology - Body mass index is associated with cardiovascular disease and type 2 diabetes risk

Diabetes Epidemiology - Diabetes risk and birth size link not altered by insulin gene variant or HLA-DQ genotype

Diabetes Mellitus - MannKind completes enrollment in phase III study of Technosphere Insulin

Diabetes Model - Human insulin resistance is mimicked by O-GlcNAcase (oga-1) knockout in Caenorhabditis elegans

Diabetes Pathogenesis - CART is a novel islet regulatory peptide

Diabetes Pathogenesis - Chemical chaperones reduce endoplasmic reticulum stress and restore glucose homeostasis

Diabetes Pathogenesis - Diabetes-related changes in brain function may be mediated by cell death and proliferation

Diabetes Pathogenesis - Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetes

Diabetes Pathogenesis - Health behaviors of mothers with gestational diabetes history were investigated

Diabetes Pathogenesis - In diabetes, ACE or AT-2 inhibitors are linked to impaired cardiovascular and renal health

Diabetes Pathogenesis - In prediabetes, soluble P-selectin may not contribute to prothrombotic state or atherogenesis

Diabetes Pathogenesis - Insulin-elicited tyrosine phosphorylation is extensive and may involve unrecognized proteins

Diabetes Pathogenesis - Systemic immune mediators appear to be associated with type 2 diabetes progression

Diabetes Research - Insulin-receptor activation assay miniaturized

Diabetes Research - Joslin Diabetes Center partners with drugstore chain for diabetes awareness and education

Diabetes Research - Poor quality sleep linked to reduced control of blood-sugar levels in people with diabetes

Diabetes Research - Study shows leptin could combat type 2 diabetes

Diabetes Therapy - Autologous serum leads to faster corneal epithelial abrasion closure in diabetics

Diabetes Therapy - Glibenclamide and inhaled human insulin equally effective in improving glycemic control

Diabetes Therapy - Higher utilization of various antihyperglycemic drugs seen for type 2 diabetes

Diabetes Therapy - Insulin detemir and NPH show linear dose-response relationship among type 2 diabetics

Diabetes Therapy - New diabetes guidelines target foot complications, amputations

Diabetes Therapy - Polyphenols improve AMPK, lipid levels, and accelerated atherosclerosis in diabetes model

Diabetes Therapy - Takeda's Actos demonstrates improvements in cardiovascular outcomes for patients with diabetes

Diabetes Therapy - Tetrahydrocurcumin showed antihyperlipidemic and antidiabetic effect in type 2 diabetic rats

Diabetic Foot Ulcer - Morbidity and mortality in diabetic foot disease underestimated by ulcer-related outcomes

Diabetic Neuropathy - Diabetic neuropathy may be irreversible despite metabolic and vascular risk marker improvements

Diabetic Retinopathy - Different diabetic macular edema treatments offer comparable results in early studies

Diagnostics - Lipomics receives U.S. Department of Defense grant for study using lipid analysis to assess fitness

Diet & Nutrition - Dorsomedial hypothalamic nucleus may play key role as central food-entrainable oscillator

Diet & Nutrition - Low-fat vegan diet improves glycemic control and cardiovascular risk in type 2 diabetes

Diet & Nutrition - Nutrigenomics may result in biomarker discovery in nutrition and health

Endocannabinoid - Peripheral endocannabinoid overactivity may explain CB₁ blocker-related weight loss in obese

Endocrinology - Insulin aspart intrasubject variations between injections is acceptable

Endocrinology - Insulin downregulates angiopoietin-like protein 4 mRNA in 3T3-L1 adipocytes

Endocrinology - Low visfatin/pre-B cell colony-enhancing factor in obesity not linked to insulin resistance

Fitness & Wellness - Modifying carbohydrate glycemic index of meals changes hyperinsulinemic response in women

Fitness & Wellness - New method to calculate energy expenditure using total body fat is proposed

Fitness & Wellness - People with disabilities are less healthy than those without disabilities

Genetics & Genomics - Glycation gap heritability accounts for about one-third of HbA_1c heritability

Glucose Homeostasis - Enhanced leptin sensitivity and improved glucose homeostasis seen in mice lacking Soc-3

HIV/AIDS Diet & Nutrition - Micronutrient supplementation increases CD4 counts in HIV-infected patients on HAART

Health Promotion - Highmark launches 5-year, $100 million initiative to improve kids' health and well being

Hepatocellular Carcinoma - Hepatocellular carcinoma risk factors clarified for patients with cirrhosis

Hyperglycemia - Glycemic instability is underestimated in type 2 diabetes

Hyperglycemia - Hyperglycemia alters PI3k and Akt signaling

Hyperglycemia - N-Acetylcysteine improves dyslipidemia, hyperglycemia and oxidative stress in high-sucrose diet

Hyperthyrotropinemia - Hyperthyrotropinemia in young obese is reversible after weight loss and is not lipids related

Insulin Delivery - Insulin pulmonary delivery may be possible with cyclodextrin particles

Insulin Research - Insulin-induced glucose uptake by 3T3-L1 adipocytes is raised by chromium plus vanadate

Insulin Resistance - Astellas begins screening another target from Metabolex gene database

Insulin Resistance - Impaired fasting glucose and impaired glucose tolerance mechanisms are studied

Insulin Resistance - Obese changes in morphology of mitochondria can improve insulin resistance

Insulin Resistance - Poor glycemic control in diabetes linked to insulin resistance and altered endocrine function

Kidney Disease - New treatment a success for anemia associated with chronic kidney disease

Legal Issues - Unimed Pharmaceuticals settles AndroGel litigation with Watson Pharmaceuticals, Paddock Labs

Market Analysis - Antidiabetic glitazar market uncertain after five companies cease development, report finds

Mental Health - Antipsychotic-induced obesity model was developed in male rats

Metabolic Syndrome - Adipocyte fatty acid binding protein may be independent metabolic syndrome marker

Metabolic Syndrome - New study shows grape seed extract has beneficial effect on metabolic syndrome

Nephrology - Adipokine levels change during treatment for nonalcoholic steatohepatitis

Obesity & Infertility - Infertility program aids overweight patients

Obesity Complications - Blood pressure increases after aldosterone infusion with high-NaCl diet in obese rats

Obesity Complications - Plasma free fatty acids may exert a lipotoxic effect on the heart

Obesity Complications - PPAR gamma ligand pioglitazone can induce plasminogen activator inhibitor-1 expression

Obesity Epidemiology - Genetics of human obesity were reviewed

Obesity Epidemiology - Ghrelin and peptide YY dynamics may predict race-related differences in obesity risk

Obesity Epidemiology - Globally people are increasing fat intake while reducing fiber intake and energy expenditure

Obesity Epidemiology - Interleukin-6-deficient mice show lower stress- and cold-induced increase in energy expenditure

Obesity Epidemiology - Obesity and insulin resistance are decided more so by postnatal environment

Obesity Epidemiology - Obesity rate is higher among minorities but community poverty impacts obesity in Whites more

Obesity Epidemiology - Physical activity, measured by pedometer, linked to body composition in children

Obesity Prevention - Physical activity of vigorous intensity may prevent obesity