Obesity Pathogenesis
In obese, Tanner stage G1PH1 boys the inhibin B/FSH axis is activated early
Published in Obesity and Diabetes Week, October 9th, 2006
In a recent study, researchers in People's Republic of China conducted a study "to determine whether early activation of the inhibin B/FSH axis is detectable in prepubertal obese boys. Thirty-five simple obese Tanner stage G1PH1 boys with body mass index over 25 aged 8-11 years old and 25 age-matched nonobese healthy prepubertal boys (G1PH1) were clinically examined and testicular size measured by ultrasound."
"Serum inhibin B, testosterone, LH, FSH, dehydroepiandrosterone (DHEA), DHEA sulfate (DHEAS) and bone age were measured. GnRH-stimulating tests were performed in the...
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