Diabetes & Proteomics
p38 mitogen-activated protein kinase mediates FFA-induced gluconeogenesis in hepatocytes
Published in Obesity and Diabetes Week, October 16th, 2006
"Free fatty acids (FFA) are considered as a causative link between obesity and diabetes. In various animal models and in humans FFA can stimulate hepatic gluconeogenesis. Although the in vivo role of FFA in hepatic gluconeogenesis has been clearly established, the intracellular role of FFA and related signaling pathway remain unclear in the regulation of hepatic gluconeogenic gene transcription," scientists in the United States report.
"In this study," proposed Q.F. Collins and colleagues at the Chemical Industry Institute of Toxicology Centers for...
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