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Obesity and Diabetes Week

Susan Hasty, Publisher

Table of Contents . . . October 23rd, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Obesity and Diabetes Week | Other Publications

Diabetes & Obesity - Insulin-resistance is closely associated with metabolic syndrome components in obese

Diabetes & Obesity - Pro12Ala variant of PPAR-gamma2 gene is linked to high diastolic blood pressure in obese diabetics

Obesity Complications - Circulating MCP-1 and IL-8 levels are elevated in obese and linked to obesity-related parameters

Obesity Epidemiology - Hormone-sensitive lipase C-60G promoter variant linked to waist circumference in nonobese

Abdominoplasty - Obesity at time of abdominoplasty impacts wound complication rate following surgery

Alzheimer Disease - Kurve Technology reports clinical success in Alzheimer disease study

Amyotrophic Lateral Sclerosis - CytRx's Arimoclomol meets primary safety and tolerability endpoints in Phase IIa ALS clinical trial

Angina - Variant angina and significant coronary stenosis often resemble acute coronary syndrome

Autoimmune Diseases - PTPN22 plays an important role in type 1 diabetes and other autoimmune diseases

Cardiomyocytes - Circadian clock within cardiomyocyte is essential for heart responsiveness to fatty acids

Cardioprotection - Low-calorie cranberry juice intake improves HDL-cholesterol levels in abdominally obese men

Cardiovascular Disease - Dietary diversity score was inversely related to cardiovascular risk factors in adults

Cardiovascular Disease - Myocardial perfusion scintigraphy may be diagnostic tool for asymptomatic patients with diabetes

Cardiovascular Disease - Screening asymptomatic diabetics for coronary artery disease may not be cost effective

Cataracts - Repeated intravitreal triamcinolone injections lose efficacy in diabetic macular edema

Collaborations - Arena Pharmaceuticals reports Ortho-McNeil extends research term

Diabetes & Angiology - Cutting balloon angioplasty is effective for diabetic patients with in-stent restenosis

Diabetes Complications - Diabetes is linked to higher passive ankle stiffness and lower dorsiflexion range of motion

Diabetes Complications - Diabetes mellitus reduces the antiarrhythmic effect of ion channel blockers

Diabetes Complications - Diabetes prevalence predict demand for hospital services overall

Diabetes Complications - Diabetes raises adverse neurocognitive outcome after coronary artery bypass grafting surgery

Diabetes Complications - Diabetic patients benefit less than nondiabetic patients from infrageniculate bypass surgery

Diabetes Complications - Home and office blood pressure were not adequately controlled in most diabetic hypertensives

Diabetes Complications - Novel method was developed to quantify in vivo transferrin glycation in diabetes mellitus

Diabetes Complications - Patients with diabetic macular edema may be better managed with optical coherence tomography

Diabetes Complications - Patients with proliferative diabetic retinopathy may form nephropathy

Diabetes Complications - Plasma total homocysteine is a risk indicator for cardiovascular disease in diabetic children

Diabetes Complications - PPAR alpha deficiency raises risk of maternal abortion and neonatal mortality in murine pregnancy

Diabetes Complications - Prorenin receptor contributes to regulation of renal cortical COX-2 expression

Diabetes Complications - Type 2 diabetes-related mortality at older ages is lower than expected

Diabetes Control - Caloric restriction ameliorates oxidative and inflammatory effects of diabetes in the brain

Diabetes Control - Diabetes care transfer from parent to youths requires proper education and attention

Diabetes Control - Diabetes healthcare services were reduced by VA Care Coordination Home Telehealth program

Diabetes Control - Diabetes is perceived as stressful for adolescents and mothers

Diabetes Control - In a diabetic rat model, garlic oil can improve oral glucose tolerance

Diabetes Epidemiology - Pro12Ala variant of PPARG2 gene plus high intake of oleic acid is linked to type 2 diabetes

Diabetes Epidemiology - Type 2 diabetes and metabolic syndrome therapy in adolescents is often suboptimal

Diabetes Gastroparesis - In diabetic gastroparesis, vagal function and regulation of ghrelin levels are impaired

Diabetes Management - National survey shows women overlook warning signs of poor blood sugar management

Diabetes Pathogenesis - Cytoplasmic buildup of long-chain coenzyme A esters activates KATP and inhibits Kir2.1 channels

Diabetes Pathogenesis - Exercise and dexamethasone oppositely modulate beta-cell function in rat model

Diabetes Pathogenesis - Nitric oxide mediates downregulation of leptin production by 3T3-L1 adipocytes

Diabetes Pathogenesis - Perturbation of glucose flux in the liver causes hepatic insulin resistance and hyperglycemia

Diabetes Prevention - Peroxisome proliferator-activated receptor-alpha agonism prevents type 2 diabetes

Diabetes Prevention - Release of acetylcholine by Hon-Chi raises insulin secretion and may prevent type 2 diabetes

Diabetes Research - Pine tree bark reduces diabetic microangiopathy

Diabetes Therapy - Metabolic control improves after depletion of liver x receptors in mouse model

Diabetes Therapy - Multiple oral antidiabetic agents may indicate more severe, uncontrolled diabetes

Diabetes Therapy - Pancreatic islet transplants revascularize when cocultured with angiogenesis stimulators beforehand

Diabetic Dermopathy - Diabetic dermopathy is key clinical sign for more severe neuropathic impairment

Diabetic Macular Edema - MacuSight initiates first phase 1 study of sirolimus formulation for diabetic macular edema

Diabetic Myocardium - Insulin deficiency mediates expression of Hsc70 in diabetic myocardium

Diabetic Nephropathy - Angiotensin II-dependent Src and Smad1 signaling pathway is key to diabetic nephropathy

Diabetic Retinopathy - Diabetic retinopathy pathology is altered by pigment epithelium-derived factor

Diet & Nutrition - Dietary calcium regulates obesity-induced oxidative stress in mouse model

Diet & Nutrition - High fat diet did not displace dietary sugar, therefore daily energy intake increased

Diet & Nutrition - High fat diet encourages passive overfeeding

Diet & Nutrition - High glucose and CML-BSA modulate matrix metalloproteinase release in human endothelial cells

Diet & Nutrition - Inflammation and poor antioxidant defenses are related to decline of nerve conduction velocity

Diet & Nutrition - Low-carb dieters are replacing starches and sugars with vegetables

Diet & Nutrition - Nutrients mediate phosphorylation and translocation of Foxo1 in C57BL/6 and db/db mice

Diet & Nutrition - Television viewing is linked to higher consumption of unhealthy foods among youth

Diet & Nutrition - Very low-carbohydrate diet improves gastroesophageal reflux and its symptoms in obese

Drug Development - Lexicon gets U.S. Defense Department funding to identify drug targets to combat sleep deprivation

Drug Research - Obesity is associated with slower response to initial phenprocoumon therapy

Endocrinology - Insulin-like actions displayed by a naphthoquinone derivative

Endocrinology - Low plasma adiponectin levels is an independent predictors of glucose intolerance

Endocrinology - Metabolic factors can directly modulate primate somatotrope function in primate model

Endocrinology - Metformin reduces lipolysis in primary rat adipocytes stimulated by TNF-alpha or isoproterenol

Endocrinology - Proinsulin C-peptide elicits disaggregation of insulin

Finance - CytRx awarded federal grant to explore novel type 2 diabetes and obesity treatment

Fitness & Wellness - Exercise training and dietary soya protein have additive effect in reducing fat accumulation

Fitness & Wellness - Physical activity is linked to income, education, ethnic background, and commute requirements

Fitness & Wellness - Resistance exercise has a dehydroepiandrosterone sulfate-lowering effect

Fitness & Wellness - SilverSneakers Fitness members used 30% fewer healthcare services, Highmark study shows

Genetics & Genomics - Consortium develops map of vital area in major histocompatibility complex of human genome

Hearing Loss - SLC19A2 deletion causes selective inner hair cell loss and auditory neuropathy phenotype

Hyperglycemia - Antihyperglycemic activity is observed in the selective PPAR gamma modulator KR-62980

Hyperglycemia - In hyperglycemic mice, cell specificity to tolbutamide is impaired in beta-cells

Hyperglycemia - Strict glycemic control improves patient mortality and in-hospital morbidity

Hypertension - Different pathomechanisms of essential and obesity-associated hypertension are examined

Hypertension - High urinary calcium excretion in hypertension and kidney stone disease has genetic basis

Insulin Binding - Insulin binding and the active insulin receptor conformation are investigated

Insulin Release - Oleanolic acid increases acetylcholine release, which raises insulin secretion in rats

Insulin Resistance - Insulin resistance accelerates muscle wasting by activation of ubiquitin-proteasome pathway

Insulin Resistance - Nutritional determinants of insulin resistance can be used to modify diets for prevention

Insulin Therapy - Glycemic control in acute cardiac care settings reduces cost, morbidity, and mortality

Market Analysis - Type 2 diabetes drugs from Merck and Novartis predicted to become blockbusters by 2015

Mergers & Acquisitions - Matria Healthcare agrees to sell diabetes services business Dia Real in $33 million deal

Metabolic Disorders - Kalypsys nearing completion of phase Ia study of KD3010 for metabolic disorders

Natural Products - Cinnamon water extracts raise glucose uptake but inhibit adiponectin secretion in adipose cells

Natural Products - Natural products may assist in TNF-alpha-based therapies for diabetes or arthritis

Natural Products - Spices, teas, and caffeine appear to increase satiety, thermogenesis, and fat oxidation

Nephrology - Diabetic nephrology is influenced by connective tissue growth factor

Neuropathic Pain - In patients with neuropathic pain, pregabalin regimens significantly reduced pain

Neuropathic Pain - Metabolic begins recruitment for phase 2 trial of neuropathic pain drug in sciatica

Nonalcoholic Fatty Liver Disease - Isoflavone-enriched soya may be effective diet supplement for nonalcoholic fatty liver disease

Obesity Complications - Cardiovascular disease risk factors were not affected by weight if overall weight was maintained

Obesity Complications - Combined dietary-physical activity intervention improves bone strength in obese youth

Obesity Complications - Hospitalized obese have higher relative risk of subsequent affective disorders

Obesity Complications - Obesity does not adversely impact in-hospital outcomes in acute myocardial infarction

Obesity Complications - Obesity may increase the risk of Hodgkin lymphoma

Obesity Epidemiology - Obesity phenotype is linked to a gene in a region on chromosome 17q

Obesity Pathogenesis - Leptin plays autocrine role in mediating cardiomyocyte hypertrophic effects

Obesity Prevention - North Carolina's obesity prevention initiative unveils new workplace wellness campaign

Obesity Prevention - Obesity prevention programs for children and adolescents are reviewed

Obesity Study - Orexigen Therapeutics reports positive 24-week results for Contrave Phase III obesity study

Obesity Surgery - Bariatric surgery patients should make sure they are absorbing medications and nutrients

Obesity Therapy - Antiobesity effects of epsilon-polylysine are due to inhibition of dietary fat absorption

Obesity Therapy - Exenatide (Exendin-4) reduces body weight gain in normal, high-fat-fed rodents

Obesity Therapy - Hypercapnia improves tissue oxygenation in morbidly obese surgical patients

Obesity Therapy - Texas surgeons' group backs county's decision to offer bariatric surgery to obese employees

Obesity Therapy - Tonsillectomy improved obese obstructive sleep apnea syndrome with tonsil hypertrophy

Oncology - Metabolic syndrome was present in more than 50% of men with prostate cancer undergoing ADT

Ophthalmology - Pascal photocoagulation offers increased speed and precision over conventional methods

Parkinson Disease - Parkinson disease side-effects are produced by subthalamic stimulation

Pediatric Diabetes - Study finds one in 523 U.S. children and adolescents have diabetes

Pediatric Obesity - Hospital launches program to combat childhood obesity starting at birth

Pediatric Obesity - One-third of U.S. youth are not physically fit

Philanthropy - Greater Philadelphia McDonald's awards $15,000 to local schools' health and fitness programs

Sleep Apnea - Obstructive sleep apnea parameters for medical therapy are focus of review

Tobacco Use - Maternal smoking influences birthweight through interactions between fetal HLA-DQ alleles

Toxicology - Methylmercury induces pancreatic beta-cell apoptosis and dysfunction

Toxicology - Pyridoxylidene aminoguanidine does not show cytotoxic effect on B-HEF-2 cells

Type 2 Diabetes - Renal glucose excretion increases with increasing blood glucose in type 2 diabetes

Vascular Disease - QuatRx starts Phase I trial for treatment to reduce LDL cholesterol and lipoprotein

Vascular Surgery - HbA1c levels can predict complications in both nondiabetic and diabetic vascular patients

Weight Management - Food insecurity is associated with weight control practices in adolescents

Atherosclerosis - Recent findings from the United States, Japan and Spain illuminate research in atherosclerosis

Breast Cancer - Findings from the United States and describe new data in breast cancer research

Breast Cancer - Studies from the United States, Scotland and Spain advance knowledge in breast cancer research

Diabetes - Data from Germany, Israel and the United States advance knowledge in diabetes research

Diabetes - Data from Spain and Denmark advance knowledge in diabetes research

Diabetes - Data from the United States advance knowledge in diabetes research

Diabetes - Data from the United States, Italy and Brazil advance knowledge in diabetes research

Diabetes - Findings from Austria and the United States describe new data in diabetes research

Diabetes - Findings from Japan advance knowledge in diabetes research

Diabetes - Findings from Norway, the United States and Germany advance knowledge in diabetes research

Diabetes - Findings from the United States advance knowledge in diabetes research

Diabetes - New data from Australia, Switzerland and the South Korea lluminates research in diabetes

Diabetes - New findings from Denmark, the United States and Taiwan in the area of diabetes described

Diabetes - New findings from Germany, Australia and the United States in the area of diabetes detailed

Diabetes - New findings from Japan, Netherlands and Ireland in the area of diabetes described

Diabetes - New findings from Japan, the United States and Germany in the area of diabetes described

Diabetes - New findings from Taiwan, Japan and Switzerland in the area of diabetes described

Diabetes - New findings from the United States and Japan in the area of diabetes detailed

Diabetes - New findings in diabetes described from Japan, the People's Republic of China and Denmark

Diabetes - New findings in diabetes described from the United States and Netherlands

Diabetes - New findings in diabetes described from the United States and Spain

Diabetes - New research from the United Kingdom, People's Republic of China and Taiwan in the area of diabetes detailed

Diabetes - New research from the United States and Japan in the area of diabetes detailed

Diabetes - Recent findings from Portugal, Sweden and Spain illuminate research in diabetes

Diabetes - Recent findings from the United States, United Kingdom and Netherlands illuminate research in diabetes

Diabetes - Recent findings in diabetes described by researchers from Italy, Taiwan and Australia

Diabetes - Recent findings in diabetes described by researchers from the United Kingdom, United States and Brazil

Diabetes - Recent findings in diabetes described by researchers from the United States and Canada

Diabetes - Recent studies from the United States and Italy add new data to diabetes research

Diabetes - Reports from Canada, Ghana and the United States advance knowledge in diabetes research

Diabetes - Reports from Italy, Denmark and the United States describe recent advances in diabetes research

Diabetes - Reports from Switzerland and Japan add new data to diabetes research

Diabetes - Reports from Taiwan, the United States and Italy advance knowledge in diabetes research

Diabetes - Reports from the United Kingdom and Italy add new data to diabetes research

Diabetes - Reports from the United Kingdom, Kuwait and Denmark add new data to diabetes research

Diabetes - Research from Canada, the United States and the Northern Ireland add new data to diabetes body of knowledge

Diabetes - Research from the People's Republic of China and United States in diabetes provides new insights

Diabetes - Research from the United States and France add new data to diabetes body of knowledge

Diabetes - Research from the United States and Sweden add new data to diabetes body of knowledge

Diabetes - Research from the United States, Netherlands and Japan in diabetes provides new insights

Diabetes - Researchers from Germany, Norway and Italy publish new studies and findings in the area of diabetes

Diabetes - Researchers from Italy, Austria and Israel describe findings in diabetes studies

Diabetes - Researchers from Japan provide details of new studies and findings in the area of diabetes

Diabetes - Researchers from Sweden, the United States and Brazil publish new studies and findings in the area of diabetes

Diabetes - Researchers from the United States and Finland describe findings in diabetes studies

Diabetes - Researchers from the United States, Finland and Japan report details of new studies and findings in the area of diabetes

Diabetes - Researchers from the United States, South Korea and Japan publish new studies and findings in the area of diabetes

Diabetes - Researchers' data from the United States, Canada and United Kingdom advance diabetes research

Diabetes - Researchers' findings from Poland, the People's Republic of China and Iran advance diabetes research

Diabetes - Researchers' findings from the United States, India and Taiwan advance diabetes research

Diabetes - Researchers' work from Australia, the United States and Japan adds to diabetes body of knowledge

Diabetes - Studies from Japan and Australia advance knowledge in diabetes research

Diabetes - Studies from South Korea, United States and People's Republic of China add new findings to diabetes body of knowledge

Diabetes - Studies from Sweden, Japan and the United States describe new findings in diabetes research

Diabetes - Studies from Switzerland, France and Denmark advance knowledge in diabetes research

Diabetes - Studies from the United States and People's Republic of China describe new findings in diabetes research

Diabetes - Studies from the United States, Denmark and Taiwan add new findings to diabetes body of knowledge

Diet & Nutrition - Researchers from the United States provide details of new studies and findings in the area of diet & nutrition

Endocrinology - Recent findings from the NORTH Ireland and Brazil illuminate research in endocrinology

Endocrinology - Reports from the United States, South Korea and Denmark advance knowledge in endocrinology research

Endocrinology - Researchers from Germany and the United States report details of new studies and findings in the area of endocrinology

Fitness & Wellness - Recent findings from the United States and Australia illuminate research in fitness & wellness

HIV/AIDS - New findings from Spain and the United States in the area of HIV/AIDS detailed

Heart Disease - Reports from the United States describe recent advances in heart disease research

Heart Disease - Research from the United States and Serbia Montenegro add new data to heart disease body of knowledge

Heart Disease - Studies from Canada and the United States advance knowledge in heart disease research

Hepatitis C Virus - Findings from the United Kingdom and Italy describe new data in hepatitis C virus research

Obesity - Data from Sweden, India and Japan advance knowledge in obesity research

Obesity - Findings from Germany, the United States and Italy in obesity provide new insights

Obesity - Findings from Japan, the United States and France advance knowledge in obesity research

Obesity - Findings from the United States and Spain advance knowledge in obesity research

Obesity - New data from the United States, Italy and Australia lluminates research in obesity

Obesity - New findings from Japan, Brazil and Sweden in the area of obesity described

Obesity - New findings from Netherlands, France and United Kingdom in the area of obesity detailed

Obesity - New findings from the United States and Canada in the area of obesity described

Obesity - New findings in obesity described from Japan, Turkey and the South Korea

Obesity - New findings in obesity described from the United States and Japan

Obesity - New research from Japan, the United States and Germany in the area of obesity detailed

Obesity - Recent findings from the United States and Austria illuminate research in obesity

Obesity - Recent findings in obesity described by researchers from the United States, France and Turkey

Obesity - Recent studies from Italy, Austria and Chile add new data to obesity research

Obesity - Reports from the United States, Switzerland and Greece describe recent advances in obesity research

Obesity - Researchers from Australia, the United Kingdom and the United States publish new studies and findings in the area of obesity

Obesity - Researchers' findings from the United Kingdom, United States and Sweden advance obesity research

Obesity - Researchers' findings from the United States, South Korea and Canada advance obesity research

Obesity - Studies from the United States add new findings to obesity body of knowledge

Obesity - Studies from the United States and Canada advance knowledge in obesity research

Surgery - Researchers from Australia, Austria and the United States detail new studies and findings in the area of surgery

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