Obesity Therapy
Exenatide (Exendin-4) reduces body weight gain in normal, high-fat-fed rodents
Published in Obesity and Diabetes Week, October 23rd, 2006
"Exenatide (exendin-4) is an incretin mimetic currently marketed as an antidiabetic agent for patients with type 2 diabetes. In preclinical models, a reduction in body weight has also been shown in low-fat-fed, leptin receptor-deficient rodents," researchers in the United States report.
C.M. Mack and colleagues at Amylin Pharmaceutical proposed, "To more closely model the polygenic and environmental state of human obesity, we characterized the effect of exenatide on food intake and body weight in high-fat-fed, normal (those with an intact leptin signaling system) rodents....
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Obesity and Diabetes Week
More Articles from Obesity and Diabetes Week
- Diabetes & Obesity
Insulin-resistance is closely associated with metabolic syndrome components in obese - Diabetes & Obesity
Pro12Ala variant of PPAR-gamma2 gene is linked to high diastolic blood pressure in obese diabetics - Obesity Complications
Circulating MCP-1 and IL-8 levels are elevated in obese and linked to obesity-related parameters - Obesity Epidemiology
Hormone-sensitive lipase C-60G promoter variant linked to waist circumference in nonobese - Abdominoplasty
Obesity at time of abdominoplasty impacts wound complication rate following surgery - Alzheimer Disease
Kurve Technology reports clinical success in Alzheimer disease study - More from this issue of Obesity and Diabetes Week
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
