Obesity Pathogenesis
Ghrelin is involved in short- and long-term regulation of appetite and body weight
Published in Obesity and Diabetes Week, October 30th, 2006
According to a recent review from the United States, "Ghrelin, an acylated upper gastrointestinal peptide, is the only known orexigenic hormone. Considerable evidence implicates ghrelin in mealtime hunger and meal initiation."
D.E. Cummings at the University of Washington explained, "Circulating levels decrease with feeding and increase before meals, achieving concentrations sufficient to stimulate hunger and food intake. Preprandial ghrelin surges occur before every meal on various fixed feeding schedules and also among individuals initiating meals voluntarily...
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