Obesity Pathogenesis
Rosiglitazone promotes adipocyte population from bone marrow-derived circulating progenitor cells
Published in Obesity and Diabetes Week, December 18th, 2006
Dwight Klemm and colleagues transplanted mice with bone marrow marked with a fluorescent protein and found that when these mice were treated with the drug rosiglitazone (which is used to treat individuals with type 2 diabetes) adipocytes expressing the fluorescent marker could be detected in the adipose tissue.
Feeding the transplanted mice with a high-fat diet had a...
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