Published in Obesity and Diabetes Week, January 29th, 2007
Study 1: A report, "Defective hepatic regeneration after partial hepatectomy in leptin-deficient mice is not rescued by exogenous leptin," is newly published data in Laboratory Investigation. "Liver regeneration after partial hepatectomy (PH) is impaired in leptin-deficient ob/ob mice. Here, we tested whether exogenous leptin and/or correction of the obese phenotype (by food restriction or long-term leptin administration) would rescue hepatocyte proliferation and whether the hepatic progenitor cell compartment was activated in leptin-deficient ob/ob livers after PH," researchers in...
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