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Obesity and Diabetes

Data on obesity and diabetes in children reported by researchers at Sungkyunkwan University

Published in Obesity and Diabetes Week, February 5th, 2007

A new study, "Obestatin is not elevated or correlated with insulin in children with Prader-Willi syndrome," is now available. "Obestatin is a peptide hormone derived from the proteolytic cleavage of ghrelin preprohormone. In Prader-Willi syndrome (PWS), the levels of total ghrelin (TG) and acylated ghrelin (AG) are increased, and these hormones are regulated by insulin," scientists in Seoul, Korea report.

"Our objective was to analyze the changes in the obestatin levels after glucose loading and to characterize the correlations of obestatin with TG, AG, and insulin. Plasma obestatin, TG, AG, and insulin levels were measured in PWS children (n=15) and controls (n=18)...

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