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Obesity Research

Protein proves to be major link in brain-obesity puzzle

Published in Obesity and Diabetes Week, February 19th, 2007

A single protein in brain cells may act as a linchpin in the body's weight-regulating system, playing a key role in the flurry of signals that govern fat storage, sugar use, energy balance and weight, University of Michigan Medical School researchers report.

And although it's far too early to say how this protein could be useful in new strategies to fight the world's epidemic of obesity, the finding gives scientists an important system to target in future research and the development of anti-obesity medications.

In a recent issue of the Journal of Clinical Investigation, U-M researcher Liangyou Rui, PhD and his team report their findings on a...

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