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Diabetic Macular Edema

ICo Therapeutics receives U.S. FDA clearance to initiate trial in diabetic macular edema

Published in Obesity and Diabetes Week, February 19th, 2007

ICo Therapeutics Inc. announced that the United States Food and Drug Administration (FDA) has accepted the investigational new drug (IND) application for iCo-007 to treat diabetic macular edema.

"The success of our IND application brings iCo one step closer to creating an effective treatment for diabetic macular edema," said Andrew Rae, president and CEO of iCo Therapeutics.

Designed and discovered by Isis Pharmaceuticals Inc., iCo-007 is a second-generation antisense drug that targets c-Raf kinase messenger RNA. ICo-007 is expected to decrease the edema in the retina by decreasing the signaling of various growth factors such as VEGF that signal...

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