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Obesity Genetics

Data on obesity genetics discussed by researchers at National Taiwan University, Institute of Microbiology and Biochemistry

Published in Obesity and Diabetes Week, February 19th, 2007

New research, "Changes in liver PPARalpha mRNA expression in response to two levels of high-safflower-oil diets correlate with changes in adiposity and serum leptin in rats and mice," is the subject of a report. According to recent research published in the Journal of Nutritional Biochemistry, "The ligand-dependent transcription factor peroxisome proliferator-activated receptor alpha (PPARalpha) is known to be activated by common fatty acids and to regulate the expression of genes of various lipid oxidation pathways and transport. High-fat diets provide more fatty acids, which presumably could enhance lipid catabolism through up-regulation of PPARalpha signaling."

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