Obesity and Diabetes
Researchers from INSERM describe findings in obesity and diabetes
Published in Obesity and Diabetes Week, February 26th, 2007
A new study, "Enigma interacts with adaptor protein with PH and SH2 domains to control insulin-induced actin cytoskeleton remodeling and glucose transporter 4 translocation," is now available. "APS (adaptor protein with PH and SH2 domains) initiates a phosphatidylinositol 3-kinase-independent pathway involved in insulin-stimulated glucose transport. We recently identified Enigma, a PDZ and LIM domain-containing protein, as a partner of APS and showed that APS-Enigma complex plays a critical role in actin cytoskeleton organization in fibroblastic cells," scientists writing in the journal Molecular Endocrinology report.
"Because actin rearrangement is important for...
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