Obesity and Diabetes

New obesity and diabetes findings from Beth Israel Deaconess Medical Center, Division of Endocrinology published

Published in Obesity and Diabetes Week, March 19th, 2007

Research findings, "Melanin concentrating hormone is a novel regulator of islet function and growth," are discussed in a new report. "Melanin concentrating hormone (MCH) is a hypothalamic neuropeptide known to play a critical role in energy balance. We have previously reported that overexpression of MCH is associated with mild obesity," scientists writing in the journal Diabetes report.

"In addition, mice have substantial hyperinsulinemia and islet hyperplasia that is out of proportion with their degree of obesity. In this study, we further explored the role of MCH in the endocrine pancreas. Both MCH and MCHR1 are expressed in mouse and human islets and in clonal...

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Source: Obesity and Diabetes Week (2007-03-19)

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