Obesity and Diabetes Genetics
Reports on obesity and diabetes genetics findings from Wayne State University provide new insights
Published in Obesity and Diabetes Week, March 19th, 2007
Investigators publish new data in the report "Depletion of CD4+CD25+ regulatory T cells exacerbates sodium iodide-induced experimental autoimmune thyroiditis in human leucocyte antigen DR3 (DRB1*0301) transgenic class II-knock-out non-obese diabetic mice." According to recent research from the United States, "Both genetic and environmental factors contribute to autoimmune disease development. Previously, we evaluated genetic factors in a humanized mouse model of Hashimoto's thyroiditis (HT) by immunizing human leucocyte antigen DR3 (HLA-DR3) and HLA-DQ8 transgenic class II-knock-out non-obese diabetic (NOD) mice."
"DR3+ mice were susceptible to experimental autoimmune...
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