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Obesity Therapy

Sungkyunkwan University, College of Pharmacy reports research in obesity therapy

Published in Obesity and Diabetes Week, April 16th, 2007

A report, "Pharmacokinetics of 125I-GST-TatdMt, a recombinant fusion protein possessing potent anti-obesity activity, after intravenous, nasal, oral, and subcutaneous administration," is newly published data in Regulatory Peptides. "This study first reports the absorption kinetics of GST-TatdMt, a recombinant Tat protein possessing potent anti-obesity activity, in rats after nasal, s.c., and p.o. administration. GST-TatdMt was over-expressed in E. coli, purified, and radioiodinated using the IODO-GEN method," researchers in Korea report.

"The radioiodinated 125I-GST-TatdMt was administered to rats by nasal, s.c., and oral routes at doses of 7.3 microg...

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