Obesity and Diabetes Genetics
New obesity and diabetes genetics research from Cedars-Sinai Medical Center discussed
Published in Obesity and Diabetes Week, July 16th, 2007
Investigators publish new data in the report "SORCS1: a novel human type 2 diabetes susceptibility gene suggested by the mouse." According to a study from the United States, "A small number of susceptibility genes for human type 2 diabetes have been identified by candidate gene analysis or positional cloning. Genes found to influence diabetes or related traits in mice are likely to be susceptibility genes in humans."
"SorCS1 is the gene identified as responsible for the mouse chromosome 19 T2dm2 quantitative trait locus for fasting insulin levels, acting via impaired insulin secretion and increased islet disruption in obese females. Genes that impair compensatory...
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