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Angiogenesis

Investigators at Louisiana State University, Pennington Biomedical Research Center target angiogenesis

Published in Obesity and Diabetes Week, July 16th, 2007

A new study, "An assay to measure angiogenesis in human fat tissue," is now available. "Inhibition of angiogenesis reverses rodent obesity. A validated assay in human fat tissue is needed to study the role of angiogenesis in human obesity," scientists in the United States report.

"Human fat tissue fragments from surgery were placed in 96-well plates, embedded in fibrin thrombin clot and overlaid with cell culture media containing 20% fetal bovine serum. After 15 days, the clots were examined by histology and electron microscopy. The effect of taxol, cobalt chloride and a heparin-steroid combination was tested in the fat tissue assay and compared to the validated human...

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