Obesity and Diabetes
Research in the area of obesity and diabetes reported from Paracelsus Private Medical University, Department of Laboratory Medicine
Published in Obesity and Diabetes Week, July 23rd, 2007
Fresh data on obesity and diabetes are presented in the report "The SREBF-1 locus is associated with type 2 diabetes and plasma adiponectin levels in a middle-aged Austrian population. The sterol regulatory element-binding protein-1c (SREBP-1c) is a transcription factor involved in the regulation of lipid and glucose metabolism and has been implicated in the pathophysiology of type 2 diabetes mellitus (T2DM). We aimed to confirm associations of the SREBF-1 gene with T2DM in an Austrian population and to study possible associations with diabetes-related quantitative traits. S AND We genotyped a diabetic cohort (n=446) along with a control group (n=1524) for a common C/G variation that is...
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