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Obesity and Diabetes

New blood test might offer early warning of deep belly fat

Published in Obesity and Diabetes Week, July 23rd, 2007

Measuring levels of a chemical found in blood offers the best indicator yet of the amount of fat surrounding abdominal organs, according to a new study of lean and obese individuals reported in Cell Metabolism, a publication of Cell Press. The buildup of such “visceral fat” is of particular health concern as it has been linked to insulin resistance, type 2 diabetes, and heart disease risk.

The researchers, including Barbara Kahn and Timothy Graham of Harvard Medical School and Matthias Blüher of the University of Leipzig in Germany, showed that “retinol-binding protein 4” (RBP4) is produced in much greater amounts by visceral fat compared to the subcutaneous fat that...

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