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Obesity and Diabetes

Research data from University of Sao Paulo update understanding of obesity and diabetes

Published in Obesity and Diabetes Week, September 10th, 2007

"Fifteen normal-weight (body mass index (BMI) 21.50 +/- 1.65 kg/m(2)) hirsute women with polycystic ovary syndrome and normal insulin sensitivity were treated with 850 mg metformin orally, three times daily, for 4 months. Before and at the end of the treatment, clinical data as well as serum concentrations of sex steroid hormones, gonadotropins, fasting plasma glucose and insulin, insulin resistance-homeostasis model assessment (HOMA-IR), carbohydrate tolerance and the area under the curve for insulin (AUC(insulin)) were analyzed," scientists writing in the journal Gynecological Endocrinology report.

"Three patients withdrew from the study. Seven of the remaining...

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