Obesity
Burning extra calories with a 'futile protein cycle'
Published in Obesity and Diabetes Week, September 17th, 2007
Christopher Lynch of The Pennsylvania State University College of Medicine and his colleagues found that they could drive such heightened protein turnover in mice by disrupting an enzyme involved in the metabolism of some amino acids, the building blocks of proteins. The enzyme-deficient animals showed elevated blood levels of the essential amino acid leucine, an important nutrient signal, and became slimmer than normal mice despite...
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