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Obesity and Diabetes

Studies from University of Modena reveal new findings on obesity and diabetes

Published in Obesity and Diabetes Week, October 29th, 2007

"'Background Descriptions of new cases of human aromatase deficiency are useful for a better understanding of male oestrogen pathophysiology, as some aspects remain controversial. Objective To present a new case of an adult man affected by aromatase deficiency, along with a description of clinical phenotype, and hormonal and genetic analysis," researchers in Modena, Italy report.

"Case report study. Patient A 25-year-old man with continuing linear growth, eunuchoid body habitus and diffuse bone pain. Measurements Amplification and sequencing of all coding exons with their flanking intronic sequences of the CYP19A1 gene. Aromatase expression of the mutant human cDNAs was...

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