Obesity and Diabetes

Studies from Medical University of Vienna in the area of obesity and diabetes described

Published in Obesity and Diabetes Week, November 19th, 2007

According to recent research from Vienna, Austria, "Obesity is associated with a chronic low-grade inflammation and an increased abundance of macrophages in adipose tissue. Adipose tissue macrophages (ATMs) are assumed to interfere with adipocyte function leading to insulin resistance, thereby contributing to the pathogenesis of type 2 diabetes mellitus."

"Macrophages exist in separate types of differentiation, but the nature of ATMs is largely unknown. Design and measurements: Stromal vascular cells (SVCs) and ATMs were isolated from human adipose tissues from different locations. We characterized ATMs phenotypically and functionally by flow cytometry, endocytosis...

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Source: Obesity and Diabetes Week (2007-11-19)

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