Obesity

Data on obesity discussed by S. Sugita and colleagues

Published in Obesity and Diabetes Week, November 26th, 2007

"We examined the gene expression of macrophage-colony stimulating factor (M-CSF) in mice with diet-induced obesity and in genetically obese mice. We also examined the effect of decreased M-CSF signaling on the susceptibility to obesity and macrophage recruitment into the adipose tissue of mice," scientists in Tokyo, Japan report.

"Research Methods and Procedures: The adipose tissue from mice with diet-induced obesity, obese KKA(y) mice, and ob/ob obese mice was used for RNA preparation. Production of M-CSF and monocyte chemoattractant protein-1 (MCP-1) was examined by quantitative real-time polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay. The op/+...

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Source: Obesity and Diabetes Week (2007-11-26)

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