Obesity & Diabetes Week
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Obesity and Diabetes
Studies from Karolinska University reveal new findings on obesity and diabetes
December 10th, 2007
"Defective beta-cell function with resulting impairment of glucose-stimulated insulin release is a critical factor in the pathogenesis of type 2 diabetes. Accumulated studies in pancreatic islets of the spontaneously diabetic Goto-Kakizaki (GK) rat suggest that this is a useful animal model of type 2 diabetes," researchers in Stockholm, Sweden report. "The GK rat is non-obese, and abnormal glucose regulation develops early in life in association with impaired insulin secretion. There are some differences in islet morphology and function reported between different GK rat colonies. In addition to reduction of beta-cell mass, a number of beta-cell defects have been...
Source: Obesity & Diabetes Week (2007-12-10)
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