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Polycythemia Vera
Study results from Mount Sinai School of Medicine, Department of Medicine broaden understanding of polycythemia vera
December 10th, 2007
Data detailed in 'Behavior of CD34+ cells isolated from patients with polycythemia vera in NOD/SCID mice' have been presented. According to recent research from the United States, "We investigated if polycythemia vera (PV) peripheral blood (PB) CD34+ cells contain cells capable of engrafting nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice and if the JAK2V617F mutational burden of these cells alters their behavior in NOD/SCID mice. CD34+ cells isolated from patients with PV, idiopathic myelofibrosis (IM), or granulocyte colony-stimulating factor-mobilized normal donors were transplanted into sublethally irradiated NOD/SCID mice." "Cells engrafted into...
Source: Obesity & Diabetes Week (2007-12-10)
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