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Obesity & Diabetes Week

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Obesity and Diabetes



New obesity and diabetes study findings have been reported by scientists at University of Tsukuba



December 10th, 2007

"Insulin resistance is often associated with obesity and can precipitate type 2 diabetes. To date, most known approaches that improve insulin resistance must be preceded by the amelioration of obesity and hepatosteatosis," scientists in Tsukuba, Japan report.

"Here, we show that this provision is not mandatory; insulin resistance and hyperglycemia are improved by the modification of hepatic fatty acid composition, even in the presence of persistent obesity and hepatosteatosis. Mice deficient for Elovl6, the gene encoding the elongase that catalyzes the conversion of palmitate to stearate, were generated and shown to become obese and develop hepatosteatosis when fed a...


Source: Obesity & Diabetes Week (2007-12-10)

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