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Obesity and Diabetes

Research reports on obesity and diabetes from University of Kansas provide new insights

Published in Obesity and Diabetes Week, December 24th, 2007

"The aim of this work was to design and utilize a bifunctional peptide inhibitor called glutamic acid decarboxylase-bifunctional peptide inhibitor to suppress the progression of type I diabetes in non-obese diabetic mice. The hypothesis is that glutamic acid decarboxylase-bifunctional peptide inhibitor binds simultaneously to major histocompatibility complex-II and intercellular adhesion molecule type I on antigen-presenting cell and inhibits the immunological synapse formation during T-cell-antigen-presenting cell interactions," investigators in the United States report.

"Glutamic acid decarboxylase-bifunctional peptide inhibitor was composed of a major epitope of the...

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