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Research from Kyorin University in the area of life sciences described

Published in Obesity and Diabetes Week, February 11th, 2008

New research, 'Gliclazide inhibits proliferation but stimulates differentiation of white and brown adipocytes,' is the subject of a report. "Gliclazide, a second-generation sulfonylurea, has anti-oxidant properties as well as hypoglycemic activities. In the present study, we investigated whether gliclazide affected proliferation and/or differentiation of HW white and HB2 brown adipocyte cell lines," researchers in Mitaka, Japan report.

"Gliclazide inhibited proliferation of HW and HB2 cells in the medium containing fetal calf serum or epidermal growth factor (EGF). Gliclazide inhibited phosphorylation of EGF receptor and of extracellular signal-regulated kinase (ERK)...

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