Obesity and Diabetes
Research from University of Cambridge broadens understanding of obesity and diabetes
Published in Obesity and Diabetes Week, February 18th, 2008
Data detailed in 'TNF-alpha and adipocyte biology' have been presented. "Dyslipidemia and insulin resistance are commonly associated with catabolic or lipodystrophic conditions (such as cancer and sepsis) and with pathological states of nutritional overload (such as obesity-related type 2 diabetes). Two common features of these metabolic disorders are adipose tissue dysfunction and elevated levels of tumor necrosis factor-alpha (TNF-alpha)," scientists in Cambridge, the United Kingdom report.
"Herein, we review the multiple actions of this pro-inflammatory adipokine on adipose tissue biology. These include inhibition of carbohydrate metabolism, lipogenesis, adipogenesis...
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