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Type 1 Diabetes Genetics

New type 1 diabetes genetics data have been reported by scientists at University of Pittsburgh

Published in Obesity and Diabetes Week, February 18th, 2008

Scientists discuss in 'Genome-wide microarray expression analysis of CD4+ T Cells from nonobese diabetic congenic mice identifies Cd55 (Daf1) and Acadl as candidate genes for type 1 diabetes' new findings in type 1 diabetes. According to recent research published in the Journal of Immunology, "NOD.Idd3/5 congenic mice have insulin-dependent diabetes (Idd) regions on chromosomes 1 (Idd5) and 3 (Idd3) derived from the nondiabetic strains B10 and B6, respectively. NOD.Idd3/5 mice are almost completely protected from type 1 diabetes (T1D) but the genes within Idd3 and Idd5 responsible for the disease-altering phenotype have been only partially characterized."

"To...

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