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Obesity

Studies from University of Copenhagen further understanding of obesity

Published in Obesity and Diabetes Week, February 18th, 2008

A new study, 'A low-glycemic-index diet reduces plasma plasminogen activator inhibitor-1 activity, but not tissue inhibitor of proteinases-1 or plasminogen activator inhibitor-1 protein, in overweight women,' is now available. "The development of obesity has been suggested to involve plasminogen activator inhibitor-1 (PAI-1) and tissue inhibitor of proteinases-1 (TIMP-1). Plasma PAI-1 is elevated in obesity," scientists in Frederiksberg, Denmark report.

"A low-glycemic-index (LGI) diet may have a beneficial effect on obesity through a decrease in plasma PAI-1, but whether it affects plasma TIMP-1 in healthy humans has not been studied. We investigated whether a 10-wk...

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