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Obesity and Diabetes

Study data from P.C. Tsiotra and colleagues update understanding of obesity and diabetes

Published in Obesity and Diabetes Week, February 25th, 2008

"Visfatin, is a new adipokine, highly expressed in the visceral fat of both mice and humans. To examine whether visfatin is expressed in human peripheral monocyte-enriched mononuclear cells and whether its expression is altered in type 2 diabetes (DM2), we compared 24 DM2 women [17 overweight (BMI > 25) and 7 lean (BMI < 25)] to 26 healthy women (14 overweight and 12 lean), all premenopausal," scientists writing in the journal Hormone and Metabolic Research report.

"Relative visfatin mRNA levels were significantly higher (approximately 3-fold) in DM2 compared to healthy control women (p < 0.02), independently of the presence of overweight/obesity....

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