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Obesity and Diabetes Animal Studies

Department of Veterans Affairs describes research in obesity and diabetes animal studies

Published in Obesity and Diabetes Week, March 24th, 2008

Research findings, 'Treatment of cardiovascular dysfunction associated with the metabolic syndrome and type 2 diabetes,' are discussed in a new report. According to a study from the United States, "Our previous studies have shown vascular dysfunction in small coronary and mesenteric arteries in Zucker obese rats, a model of the metabolic syndrome, and Zucker Diabetic Fatty (ZDF) rats, a model of type 2 diabetes. Because of their lipid lowering action and antioxidant activity, we predicted that treatment with Rosuvastatin, an HMG-CoA reductase inhibitor (statin) or Enalapril, an angiotensin converting enzyme (ACE) inhibitor would improve vascular dysfunction associated with the metabolic...

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