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Metabolism

New data from Maastricht University, Department of Molecular Genetics illuminate research in metabolism

Published in Obesity and Diabetes Week, March 31st, 2008

A report, 'The PPARgamma ligand rosiglitazone influences triacylglycerol metabolism in non-obese males, without increasing the transcriptional activity of PPARgamma in the subcutaneous adipose tissue,' is newly published data in British Journal of Nutrition. "PPARgamma is obligatory for fat mass generation and is thought to determine the amount of TAG stored per fat cell. We investigated whether ligand availability for PPARgamma is rate limiting in fat mass generation and substrate metabolism," researchers in Netherlands report.

"Twenty healthy men (20-29 years) were randomly assigned to receive the PPARgamma ligand rosiglitazone (RSG) (8 mg/d) (n 10) or a...

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