Obesity Genetics
Studies from St. Vincent's Hospital describe new findings in obesity genetics
Published in Obesity and Diabetes Week, March 31st, 2008
Data detailed in 'PYY transgenic mice are protected against diet-induced and genetic obesity' have been presented. "The gut-derived hormone, peptide YY (PYY) reduces food intake and enhances satiety in both humans and animals. Obese individuals also have a deficiency in circulating peptide YY, although whether this is a cause or a consequence of obesity is unclear," scientists writing in the journal Neuropeptides report.
"Our aims were to determine whether peptide YY (PYY) over-expression may have therapeutic effects for the treatment of obesity by altering energy balance and glucose homeostasis. We generated PYY transgenic mice and measured body weight, food...
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