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Obesity and Diabetes

New findings from Karolinska University in the area of obesity and diabetes described

Published in Obesity and Diabetes Week, March 31st, 2008

"OBJECTAT-Visceral obesity increases risk of insulin resistance and type 2 diabetes. This may partly be due to a region-specific resistance to insulin's antilipolytic effect in visceral adipocytes," scientists writing in the journal Diabetes report.

"We investigated whether adipose tissue releases the vascular peptide endothelin-1 (ET-1) and whether ET-1 could account for regional differences in lipolysis. One group consisted of eleven obese and eleven nonobese subjects in whom ET-1 levels were compared between abdominal subcutaneous and arterialized blood samples. A second group included subjects undergoing anti-obesity surgery. Abdominal subcutaneous and...

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