Obesity

New findings from M. Nilsson and co-authors in the area of obesity published

Published in Obesity and Diabetes Week, April 7th, 2008

According to recent research from Huddinge, Sweden, "The estrogen receptors alpha and beta (ESR1, ESR2) have been implicated in adiposity, lipid metabolism and feeding behaviour. In this report we analyse ESR1 and ESR2 gene single nucleotide polymorphisms (SNPs) for association with obesity."

"We also relate adipose tissue ESR1 mRNA levels and ESR1 SNPs to adipocyte lipolysis and lipogenesis phenotypes. 23 ESR1 and 11 ESR2 tag-SNPs, covering most of the common haplotype variation in each gene according to HAPMAP data, were analysed by Chi(2) for association with obesity in a cohort comprising 705 adults with severe obesity and 402 lean individuals. Results were...

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Source: Obesity and Diabetes Week (2008-04-07)

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