Insulin Resistance

Investigators at University of Lausanne, Department of Physiology release new data on insulin resistance

Published in Obesity and Diabetes Week, April 14th, 2008

New research, 'Effects of four-week high-fructose diet on gene expression in skeletal muscle of healthy men,' is the subject of a report. According to a study from Lausanne, Switzerland, "A high-fructose diet (HFrD) may play a role in the obesity and metabolic disorders epidemic. In rodents, HFrD leads to insulin resistance and ectopic lipid deposition."

"In healthy humans, a four-week HFrD alters lipid homoeostasis, but does not affect insulin sensitivity or intramyocellular lipids (IMCL). The aim of this study was to investigate whether fructose may induce early molecular changes in skeletal muscle prior to the development of whole-body insulin resistance. Muscle...

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Source: Obesity and Diabetes Week (2008-04-14)

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