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Johns Hopkins Medical Institutions

Study in 7,000 men and women ties obesity, inflammatory proteins to heart failure risk

Published in Obesity and Diabetes Week, May 19th, 2008

Heart specialists at Johns Hopkins and elsewhere report what is believed to be the first wide-scale evidence linking severe overweight to prolonged inflammation of heart tissue and the subsequent damage leading to failure of the body's blood-pumping organ.

The latest findings from the Multiethnic Study of Atherosclerosis (MESA), to be published in the May 6 issue of the Journal of the American College of Cardiology, appear to nail down yet one more reason for the estimated 72 million obese American adults to be concerned about their health, say scientists who conducted the research.

"The biological effects of obesity on the heart are quite profound,"...

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