Apoptosis

New apoptosis research has been reported by scientists at Catholic University

Published in Obesity and Diabetes Week, June 23rd, 2008

According to a study from Rome, Italy, "Lipoapoptosis has been described in many organs and tissues, but never in enterocytes. We hypothesized that a high saturated-fat diet can induce duodenal enterocyte apoptosis and impair gastric inhibitory polypeptide (GIP) secretion."

"Forty male Wistar rats, similar to 4 months old, were randomized on standard laboratory or purified tripalmitin-based high-fat diet (59% calories). An oral-glucose tolerance test was performed after 30 and 90 days of diet to measure plasma glucose, insulin and GIP. Duodena were processed for histology and immunohistochemistry by transferase-mediated dUTP nick end-labeling (TUNEL) method. Apoptosis...

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Source: Obesity and Diabetes Week (2008-06-23)

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