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Angiology

Research reports from University of Zurich provide new insights into angiology

Published in Obesity and Diabetes Week, June 30th, 2008

Researchers in Zurich, Switzerland conducted a study "To determine effects of dietary fat content on vascular responses in different conduit arteries in mice. Vascular responses to reactive oxygen species ( ROS)/ hydroxyl radical (center dot OH), acetylcholine ( ACh), endothelin-1 ( ET-1), and angiotensin II ( Ang II) were determined in carotid and femoral arteries of C57BL/ 6J mice fed with diets varying in fat content ( low fat ( LF), 12.3%; high fat ( HF), 41%; and very high fat ( VHF), 58% ( kcal from fat)) for 15 weeks, beginning at 4 weeks of age."

"In precontracted rings of carotid and femoral artery, ROS/center dot OH-induced a rapid, transient vasodilation. In...

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