Proteomics
Studies from Wayne State University in the area of proteomics described
Published in Obesity and Diabetes Week, July 21st, 2008
Researchers detail in 'Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis,' new data in proteomics. According to recent research published in the journal Endocrinology, "Signal transducer and activator of transcription (Stat)-3 signals mediate many of the metabolic effects of the fat cell-derived hormone, leptin. In mice, brain-specific depletion of either the long form of the leptin receptor (Lepr) or Stat3 results in comparable obese phenotypes as does replacement of Lepr with an altered leptin receptor locus that codes for a Lepr unable to interact with Stat3."
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