Obesity and Diabetes

New obesity and diabetes data have been reported by researchers at University of Birmingham

Published in Obesity and Diabetes Week, July 28th, 2008

According to recent research from Birmingham, the United Kingdom, "The epidemics of obesity, insulin resistance, and type 2 diabetes have heightened the need to understand mechanisms that contribute to their pathogenesis. Increased endogenous glucocorticoid production has been implicated based on parallels with Cushing's syndrome."

"We have assessed the impact of weight loss on glucocorticoid secretion and metabolism (notably 11 beta-hydroxysteroid dehydrogenase type 1 and 5 alpha-reductase [5 alpha R] activity) and insulin sensitivity. Twenty obese volunteers were investigated before and after weight loss. Patients underwent hyperinsulinemic-euglycemic clamps with...

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Source: Obesity and Diabetes Week (2008-07-28)

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