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Obesity and Diabetes

Reports outline obesity and diabetes study results from Brigham and Women's Hospital

Published in Obesity and Diabetes Week, August 4th, 2008

"Intestinal transport exhibits distinct diurnal rhythmicity. Understanding the mechanisms behind this may reveal new therapeutic strategies to modulate intestinal function in disease states such as diabetes and obesity, as well as short bowel syndrome," investigators in the United States report.

"Although diurnal rhythms have been amply documented for several intestinal transporters, the complexity of transepithelial transport has precluded definitive attribution of rhythmicity in glucose uptake to a single transporter. To address this gap, we assessed temporal changes in glucose transport mediated by the Na+/glucose cotransporter SGLT1. SGLT1 expression was assessed at...

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