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Weight Loss

New weight loss data have been reported by researchers at University of Pennsylvania

Published in Obesity and Diabetes Week, August 11th, 2008

Research findings, 'Revisiting leptin's role in obesity and weight loss,' are discussed in a new report. According to recent research published in the Journal of Clinical Investigation, "Maintenance of weight loss is often unsuccessful because of metabolic adaptations that conserve energy. Studies in rodents suggest that a reduction in leptin level during weight loss signals to the brain to increase feeding and decrease energy expenditure."

"In this issue of the JCI, Rosenbaum et al. examined this concept in obese patients who lost weight and were maintained at 10% below their initial weight (see the related article beginning on page 2583). Brain activity...

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