Diabetes
Studies from Massachusetts General Hospital add new findings in the area of diabetes
Published in Obesity and Diabetes Week, August 18th, 2008
According to a study from the United States, "OBJECTTVE-A recent meta-analysis demonstrated a nominal association of the ectonucleotide pyrophosphatase phosphodiesterase I (ENPPI) K -> Q missense single nucleotide polymorphism (SNP) at position 121 with type 2 diabetes. We set out to confirm the association of ENPP1 K121Q with hyperglycemia, expand this association to insulin resistance traits, and determine whether the association stems from K121Q or another variant in linkage disequilibrium. with it."
"We characterized the haplotype structure of ENPPI and selected 39 tag SNPs that captured 96% of common variation in the region (minor allele frequency >= 50%)...
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