Enzyme Research

Researchers from University of Ancona discuss findings in enzyme research

Published in Obesity and Diabetes Week, September 1st, 2008

"Fatty acid amide hydrolase (FAAH) inhibitors, preventing endocannabinoid (EC) degradation, reduce blood pressure (BP) and heart rate in young male (YM) hypertensive rodents. The functional human FAAH 129T gene variant results in reduced protein level and enzymatic activity but its relationship with BP is unknown," scientists writing in the American Journal of Hypertension report.

"This study investigates the relationship among FAAH P129T alleles and cardiovascular features in YMs at baseline and after 9-year follow-up, and in older male obese hypertensive (OH) patients, in whom the EC system (ECS) is overactive. Genotype analysis was performed in 215 Caucasian...

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Source: Obesity and Diabetes Week (2008-09-01)

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