Type 2 Diabetes

Studies from Erasmus University provide new data on type 2 diabetes

Published in Obesity and Diabetes Week, September 1st, 2008

According to recent research published in the journal Diabetologia, "Aims/hypothesis Retinol-binding protein 4 (RBP4), originally known for retinol transport, was recently identified as an adipokine affecting insulin resistance. The RBP4 -803GA promoter polymorphism influences binding of hepatic nuclear factor la and is associated with type 2 diabetes in case-control studies."

"We hypothesised that the RBP4 -803GA polymorphism increases type 2 diabetes risk at a population-based level. In addition, information on retinol intake and plasma vitamin A levels enabled us to explore the possible underlying mechanism. In the Rotterdam Study, a prospective,...

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Source: Obesity and Diabetes Week (2008-09-01)

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